How Cold Sores Could Hamper Memory

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The latest research shows that viral and bacterial infections could have lasting legacies on cognition.

In a recent study, researchers found that people with higher levels of common infectious agents in their blood — including Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus and herpes simplex type 1 that causes cold sores — are more likely to have memory and cognitive problems than people with lower levels.

The researchers are not the first to make the connection. Other studies have linked infections and their effects on the body, such as inflammation, disruption of lipid production, and amyloid plaque build-up, with circulatory disorders such as heart disease and stroke. And these in turn have been linked to memory disorders like Alzheimer’s and dementia. Some studies even suggested that memory loss may be a result of the brain reacting to invading infections.

(MORE: Study Shows Alzheimer’s Protein May Not Spread like a Virus)

In the latest study, researchers analyzed the memory in 1,625 people around age 69, living in New York City. They compared the scores on these cognitive tests against blood samples from the participants that detected five common infections: Herpes simplex type 1 (oral) and type 2 (genital), cytomegalovirus, the bacteria responsible for causing pneumonia, and H. pylori, which is found in the digestive tract and has been linked to inflammation in gum disease and heart disease.

Participants who had higher levels of infections were at 25% higher risk of scoring low on a cognition test called the Mini-Mental State Examination, which tested for recall. The association was strongest among women, participants with lower education levels, those on Medicaid or without health insurance, and people who did not exercise regularly. “This observation provides some indirect evidence that the negative effects of chronic infection might be mitigated by beneficial behaviors such as physical activity, and evidence is accumulating that exercise has anti-inflammatory effects,” the authors write.

The researchers continued to test the memory of the participants every year for an average of eight years, but the infections were not linked to changes in memory and thinking skills as time went on. That could mean that the the infections had already altered the memory and cognition of the participants. “The damage [was] already done at the time of enrollment,” said study author Dr. Mira Katan of the Northern Manhattan Study at Columbia University Medical Center in New York and a member of the American Academy of Neurology in an email response to questions about the results. “Another explanation would be that our duration of follow-up may have been insufficient to detect a change.”

How could infections that the body essentially fights off leave such a lasting legacy on cognition? Although the scientists aren’t sure, they have some theories. It’s possible that chronic, or persistent infections from the pathogens are leading to an overall higher level of inflammation in the body, and over time, that damage can compromise the blood vessels in the brain that contribute to making memories. Or, the infectious agents could be directly causing cognitive decline.

(MORE: New Research on Understanding Alzheimer’s)

If the link between viral and bacterial infections and memory loss disorders is confirmed with further research, it could reveal new ways of thinking about, and treating memory loss. A viral or bacterial agent that’s driving memory problems could lead to a bigger push for controlling such infections from a public health perspective, and focusing on new, antimicrobial approaches to treating disorders such as dementia or Alzheimer’s. In a corresponding editorial, Dr. Timo Strandberg of the department of medicine at the University of Helsinki, Finland and Dr. Allison Aiello, an associate professor of epidemiology at the University of Michigan School of Public Health write: “Undoubtedly, demonstrating that old-age cognitive disorders, including [Alzheimer’s disease], are slowly progressing diseases of viral etiology would revolutionize the dementia research field (and be Nobel Prize worthy). However, great challenges remain.”

One of those is the fact that no study has established conclusively that pathogens can cause cognitive decline. But the latest findings suggest that infections, and the levels of inflammation, could potentially be used to better identify at-risk populations.

“While this association needs to be further studied, the results could lead to ways to identify people at risk of cognitive impairment and eventually lower that risk. For example, exercise and childhood vaccinations against viruses could decrease the risk for memory problems later in life,” said Katan in a statement.

(MORE: Scientists Identify Rare Gene Mutation that Protects Against Alzheimer’s)

The study is published in the journal Neurology.

21 comments
ElizabethGeorge
ElizabethGeorge

Esto es real tomarlo en serio, que han de creer que una hierba puede
curar el herpes diez años en mi cuerpo, nunca creo que este
trabajará tengo gastar mucho al conseguir medicamentos de la
hospital para mantenerme sano, lo que estaba esperando es la muerte
porque yo estaba en la ruina, un día me tendido sobre este gran hombre
que es bien sabe de VIH, cáncer y anthrux cura, decidí
correo electrónico él, sin saberlo, a mí que este será el final de la
enfermedad de herpes en mi cuerpo, que prepare la hierba para mí,
y me da instrucciones sobre cómo tomar el medicamento, al final de la
semana, lo cual fue de siete días, él me dijo que fuera al hospital
para un chequeo, y fui sorprendentemente después de la prueba de la
médico a confirmar curarme de la enfermedad de herpes pensé que
Era una broma, me fui a otro hospital el médico también
confirmo curarme de la enfermedad de herpes Tomé entonces a mi
amigo que era un paciente sarna al médico después de la
tomando de las hierbas que también fue confirmar la curación de la sarna y también se sorprendió que él también curar una sarna
enfermedad .please Quiero que cada uno con este virus a ser libre,
es por eso que estoy dejando caer su dirección de correo electrónico, (spellcasterdemonictemple@gmail.com) Te quiero
correo electrónico él es un gran hombre. el gobierno es también
interesado en este doctor, gracias por salvar mi vida, y yo
prometo siempre voy a declarar por su buen trabajo. Usted puede
También enviamos un correo electrónico para saber más sobre el gran trabajo que realiza
para mí si usted está interesado en contacto con él para su propio
curar too.mrselizabeth1234@gmail.com

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AmyRossland

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GaryJames
GaryJames

been scam by fake doctors from Nigeria is another infection to herpes but getting myself cured is another joyful moment i will never forget in a life time. i was cured from herpes by Dr Mensah from Ghana who i contacted few months ago via his mail: herbalistmensahsacredherbaltemple@hotmail.com and today i am free from herpes simplex 2. i huge you to contact Dr Mensah from Ghana for your redemption from herpes via his mail address.

MancyJacob
MancyJacob

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MancyJacob
MancyJacob

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VanessaGomez
VanessaGomez

there are herbal therapies that could totally eradicate this virus from the body meanwhile there has been proofs and lots of testimonies to that effect. I took my time to investigate one Dr wadada on how his herbs magically cured my friend Anthony and his girl friend who contacted this embarrassing virus. Please do reach out to Dr. wadada via his email: WADADAHERBALHOME@gmail.com . Please don't die in pains and shame contact him now.

Ostella
Ostella

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VanessaGomez
VanessaGomez

there are herbal therapies that could totally eradicate this virus from the body meanwhile there has been proofs and lots of testimonies to that effect. I took my time to investigate one Dr wadada on how his herbs magically cured my friend Anthony and his girl friend who contacted this embarrassing virus. Please do reach out to Dr. wadada via his email: WADADAHERBALHOME@gmail.com . Please don't die in pains and shame contact him now.

MorganMary
MorganMary

I Am Mrs Johnson Morgan, i live in Texas (USA).

[READ MY STORY. ON HOW I GOT MY AIDS CURED].Truthfully, i was tested HIV + positive last 3 years. Ikeep on managing the drugs i usually purchase fromthe health care agency to keep me healthy andstressful, i tried all i can too make this diseaseleave me alone, but unfortunately, it keep on eatingup my life, this is what i caused myself, for allowingmy fiance make sex to me unsecured withoutprotection, although i never knew he is HIV positive.So last few 4 days i came in contact with a lively articleon the internet on how this Powerful Herbal Healer gether well and healed. So as a patient i knew this willtook my life 1 day, and i need to live with other friendsand relatives too. So i copied out the Dr omoye thetraditional healer's email id:dromoyespellcastertemple@outlook.com. and I mailedhim immediately, in a little while he mail me backthat i was welcome to his temple home were by allwhat i seek for are granted. I was please at that time.And i continue with him, he took some few detailsfrom me and told me that he shall get back to me assoon as he is through with my work. I was very happyas heard that from him. So Yesterday, as i was justcoming from my friends house, Dr omoye called me togo for checkup in the hospital and see his marvelouswork that it is now HIV negative, i was very glad tohear that from him, so i quickly rush down to thenearest hospital to found out, only to hear from myhospital doctor called Morgan that i am nowHIV NEGATIVE. I jump up at him with the test note, heask me how does it happen and i reside to him all iwent through with Dr omoye. I am now glad, so i am agentle type of person that need to share thistestimonies to everyone who seek for healing,because once you get calm and quiet, so the diseaseget to finish your life off. So i will advice you contacthim today for your healing at the above details: EmailID:dromoyespellcastertemple@outlook.com. CONTACTHIM NOW TO SAVE YOUR LIFE:dromoyespellcastertemple@outlook.com or call +2349034412845 AS HE IS SOPOWERFUL AND HELPFUL TO ALL THAT HAVE THISSICKNESS...

SarahAnderson
SarahAnderson

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RachelElderts
RachelElderts

Hello everyone am here to express my joy about how i got cure from a herbal doctor,i never knew i was ever going to get rid of this illness until i meet this herbal doctor called DR DADA,introduced to me by a friend of mine who also have this horrible and disgusting illness,i have tour round the hospitals all i keep hearing is that i will have to be taken much of dosage everyday just so subsidy the pain and inching and it keep having a sharp pain in the area that are affected,i couldn't bear the pain and the disgrace i have endure just to mention some view of my encounters with HSV1 AND HSV2,it is not an illness i want anyone to be infected with in fact i prefer HIV-AIDS to HSV1 AND HSV2. because you can still leave with it without thinking of the next second or minutes your body is going to start up again with all the horrible sharp biting and inching,this is how i met DR DADA introduced to me by my friend name is moore tangla re-email me that he has all it takes to get rid of any illness that the science have not be able to come up with the medication,so i press further to ask questions i start wondering how come the medication i have being taken are not responding to my immune system ,he explained everything to me that it is the wonders of the Almighty God and the FORE-FATHER who laid down everything for him when he was very little and with his hard work and proper study of ROOT AND HERBS he finally arrived at a stage where all he has labored for and study hard to understand the names of the root and herbs he started helping people to get cure just to say few because if i start i will never stop talking and writing.so after so much talk he proceed to the medication tell me how to get the HERPES medication and how to use it that after 8 days the herpes will be gone and there is nothing like side effect or after some time or years it will be reoccurring again.so i proceed to the items and he send it to me through DHL i received within a week because it takes 4 working days to get to me .so if you want to reach him just email him with his address drdadaspellhome@gmail.com or drdadaspellhome@hotmail.com  you can email me at (rachelelderts4@gmail.com)

nrhakim
nrhakim

I see an issue here and that's everyone that is seen with a cold sore will be judged as "stupid". As if we didn't have enough problems with actually having one and trying to prevent the spreading of it.

http://www.optimasi.net/

BradSoverty
BradSoverty

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MorganMaryfine
MorganMaryfine



I Am Mrs Morgan mary, i live in Texas (USA).[READ MY STORY. ON HOW I GOT MY AIDS CURED].Truthfully, i was tested HIV + positive last 3years. Ikeep on managing the drugs i usually purchase fromthe health care agency to keep me healthy andstrenghtful, i tried all i can too make this diseaseleave me alone, but unfortunately, it keep on eatingup my life, this is what i caused myself, for allowingmy fiance make sex to me unsecurely withoutprotection, although i never knew he is HIV positive.So last few 4days i came in contact with a lively articleon the internet on how this Powerful Herbal Healer gether well and healed. So as a patient i knew this willtook my life 1 day, and i need to live with other friendsand relatives too. So i copied out the Dr Oddingan thetraditional healer's email id:droddinganspellcasterhome@outlook.com, and I mailedhim immediately, in a little while he mail me backthat i was welcome to his temple home wereby allwhat i seek for are granted. I was please at that time.And i continue with him, he took some few detailsfrom me and told me that he shall get back to me assoon as he is through with my work. I was very happyas heard that from him. So Yesterday, as i was justcoming from my friends house, Dr oddingan called me togo for checkup in the hospital and see his marvelouswork that it is now HIV negative, i was very glad tohear that from him, so i quickly rush down to thenearest hospital to found out, only to hear from myhospital doctor called Morgan that i am nowHIV NEGATIVE. I jump up at him with the test note, heask me how does it happen and i recide to him all iwent through with Dr oddingan. I am now glad, so i am agentle type of person that need to share thistestimonies to everyone who seek for healings,because once you get calm and quiet, so the diseaseget to finish your life off. So i will advice you contacthim today for your healing at the above details: EmailID: droddinganspellcasterhome@outlook.com. CONTACTHIM NOW TO SAVE YOUR LIFE:droddinganspellcasterhome@outlook.com or call +2347036484707 AS HE IS SOPOWERFUL AND HELPFUL TO ALL THAT HAVE THISSICKNESS...

MikeMikez
MikeMikez

It seems to be that we should seek for cure for herpes 2015 and similar ways like this one. With herpes cure, we can have healthy life. And avoid diseases.

KyleStuart
KyleStuart

Woah! That's a hell of a lot of "suspicion". Everyone I know that suffers from cold sores, including myself, do not have any form of memory issues.


I see an issue here and that's everyone that is seen with a cold sore will be judged as "stupid". As if we didn't have enough problems with actually having one and trying to prevent the spreading of it.

lemonfoundation
lemonfoundation

Chapter 33 of Hillary Johnson's: Osler's Web: Inside the Labyrinth of the CFS Epidemic is entitled "HIV-NEGATIVE AIDS."

Neenyah Ostrom's: America's Biggest Cover-up: 50 Things...CFS Link To AIDS cites: "Some CFS Patients May Be Non-HIV AIDS Cases."

My case goes up through the NIH, CDC, White House, WHO, to the United Nations.  I have testified federally (Washington, DC), and have been published 12 times on 4 continents, my life with NON HIV AIDS:

http://ukprogressive.co.uk/the-aids-like-disease-seldom-mentioned/article20891.html

Will CFS ever make any progress unless we acknowledge this fact?

Or simply google "NON HIV AIDS"