Crazy Cat Love: Caused By Parasitic Infection?

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You like cats because they’re beautiful, elegant creatures, right? Or is it because you’ve been infected by a parasite that influences your brain?

Bizarrely, new research raises that question, finding that the parasite Toxoplasma gondii, which lives in cats, actually makes cats attractive — rather than scary — to their natural prey (in this case, rats). Earlier research also suggests that this parasite, which can infect humans, may affect personality and possibly even the risk of schizophrenia.

The one-cell critter T. gondii is probably better known as a major cause of food-borne illness (toxoplasmosis). However, the parasite doesn’t usually cause obvious disease in healthy people: some 10% of Americans carry the bug, but few have symptoms because their immune systems keep it at bay. Still, certain groups are vulnerable; if pregnant women are infected, it can cause birth defects, and the parasite can be dangerous to people with AIDS and other diseases that compromise the immune system.

While it’s possible to pick up the bug by handling dirty cat litter, T. gondii is more commonly transmitted to humans by contact with raw or undercooked meat, particularly pork.

MORE: The Science of Women and Cats: The Bond Is Real

T. gondii has a complicated life cycle. It can live in almost any mammal, but it reproduces sexually only in cats. Consequently, being able to manipulate cats’ prey — i.e., rats — so that they are more likely to be eaten is in the parasite’s genetic interest.

The new research explored rats’ response to cat urine. For obvious reasons, rats are typically terrified of cat pee, and exposure to it activates rats’ brain regions that process fear. But researchers led by Stanford’s Patrick House found that when rats with T. gondii infection were exposed to the urine, they showed activity in brain areas associated with sexual arousal instead.

This occurred only in response to urine from cats, not from other predators; the exposure also did not affect other types of fears.

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